Published Research Manuscripts

Torralva R, Janowsky A. Noradrenergic Mechanisms in Fentanyl-Mediated Rapid Death Explain Failure of Naloxone in the Opioid Crisis. Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 453-475; doi: https://doi.org/10.1124/jpet.119.258566

Waddell EN, Springer SA, Marsch LA, Farabee D, Schwartz RP, Nyaku A, Reeves R, Goldfeld K, McDonald RD, Malone M, Cheng A, Saunders EC, Monico L, Gryczynski J, Bell K, Harding K, Violette S, Groblewski T, Martin W, Talon K, Beckwith N, Suchocki A, Torralva R, Wisdom JP, Lee JD. Long-acting buprenorphine vs. naltrexone opioid treatments in CJS-involved adults. (EXIT-CJS). J Subst Abuse Treat. 2021 Sep;128:108389. doi: 10.1016/j.jsat.2021.108389. Epub 2021 Apr 8. PMID: 33865691; PMCID: PMC8384640, https://pubmed.ncbi.nlm.nih.gov/33865691/

Miner NB, Schutzer WE, Zarnegarnia Y, Janowsky A, Torralva R. Fentanyl causes naloxone-resistant vocal cord closure: A platform for testing opioid overdose treatments. Drug Alcohol Depend. 2021 Aug 28;227:108974. doi: 10.1016/j.drugalcdep.2021.108974. PMID: 34492557, https://pubmed.ncbi.nlm.nih.gov/34492557/

Torralva R, Eshleman AJ, Swanson TL, Schmachtenberg JL, Schutzer WE, Bloom SH, Wolfrum KM, Reed JF, Janowsky A. Fentanyl but not Morphine Interacts with Nonopioid Recombinant Human Neurotransmitter Receptors and Transporters. J Pharmacol Exp Ther. 2020 Sep;374(3):376-391, https://jpet.aspetjournals.org/content/374/3/376

Eshleman AJ, Nagarajan S, Wolfrum KM, Reed JF, Nilsen A, Torralva R, Janowsky A. Affinity, potency, efficacy, selectivity, and molecular modeling of substituted fentanyls at opioid receptors. Biochem Pharmacol. 2020 Dec;182:114293. doi: 10.1016/j.bcp.2020.114293. Epub 2020 Oct 20. PMID: 33091380, https://pubmed.ncbi.nlm.nih.gov/33091380/

Cook RR, Torralva R, King C, Lum PJ, Tookes H, Foot C, Vergara-Rodriguez P, Rodriguez A, Fanucchi L, Lucas GM, Waddell EN, Korthuis PT. (2021). Associations between fentanyl use and initiation, persistence, and retention on medications for opioid use disorder among people living with uncontrolled HIV disease. Drug and Alcohol Dependence, 109077, ISSN 0376-8716, https://doi.org/10.1016/j.drugalcdep.2021.109077

Submitted/Under Review

Torralva PR, Pandit-Kerr S, Kelly PJ, Pilla J, Morris K, Larsen E, Wisdom JP, Bass SB. (under review). Knowledge and perceptions of fentanyl use in people with substance use disorder at a syringe exchange and social service organization in Philadelphia, PA. Manuscript under review.

Peer Reviewed Presentations

Torralva, PR. (2021, June). An Anesthesiologist’s Perspective on Fentanyl in the Opioid Crisis. College on Problems of Drug Dependence (Symposium Moderator) via Webex. Portland, OR. 

Regional Presentations

Torralva PR. (2021, February). Fentanyl. Oregon Harm Reduction Coalition/PRIME.  Portland, OR. 

Torralva PR. (2021, February). An Animal Model of Fentanyl Toxicity. Virginia Commonwealth University -Neuropharmacology Grand Rounds via Webex. Portland, OR.  

Torralva, PR. (2021, April)). An Animal Model of Fentanyl Toxicity. NIDA/American Thoracic Society via Webex. Portland, OR. 

Torralva PR. (2021, August). An Animal Model of Fentanyl Toxicity. OHSU Department of Psychiatry Grand Rounds via Webex. Portland , OR.

Bucheit B, Larson E, Wisdom JP. (2021, September). MOMS Study. HealthShare Substance Use Disorders Researchers Breakfast. Portland, OR